Biaxial stimulation of a cells in a monolayer or 3D matrix

The MCB1 uses a complex deformable interface to generate radial motion patterns on a 24-pin mounting ring.  User-supplied 35mm diameter membranes, scaffolds, and tissues can be puncture-mounted to this ring and biaxially stretched according to the specified protocol.  The entire assembly can be sterilized and is suitable for long-term cell culture in a laboratory incubator.

Key Features

  • Biaxial stretch up to 20%
  • Compatible with a wide range of materials including silicone membranes, decellularized tissues, hydrogels, electrospun materials, and more.
  • PC-independent operation
  • User-friendly interface software for specifying simple, cyclic, and intermittent stimulation protocols for download to the device controller

We are using CellScale equipment for the last two years to assess the influence of mechanical stimulation on permanently differentiated and stem cells' fate. The interface is user-friendly, the customer support service is very helpful, the equipment is easy to use and inexpensive, yet precise and robust.

Prof. Dimitrios Zeugolis

National University of Ireland Galway

The CellScale MechanoCulture has been a very versatile bioreactor platform for us. It's size and the ability to pre-program the bioreactor conditions results in a cost-effective solution to our bioreactor needs. In addition, the software is intuitive and easy to use. CellScale has been easy to work with and has quickly addressed any issues we have come across.

Prof. Brian Amsden

Queens University


Dimensions 22 X 10 X 4cm
Weight 1kg
Stimulation Mode Biaxial tension
Configuration Cell monolayer, 3D constructs and tissues
Culture Area 1 well, 35mm diameter
Maximum Strain 20% biaxial
Maximum Velocity 10mm/s
Maximum Cycle Frequency 2Hz
Loading Capacity 10N
Media Volume/well 0.5-100mL